ALFUSIN D TAB

597.34

Alfusin D Tablet is a combination medication containing Alfuzosin (10 mg) and Dutasteride (0.5 mg), used to treat Benign Prostatic Hyperplasia (BPH) in men. Alfuzosin is an alpha-blocker that relaxes the muscles in the prostate and bladder neck, improving urine flow. Dutasteride is a 5-alpha reductase inhibitor that reduces the size of the prostate by inhibiting the hormone responsible for its growth. Together, they alleviate urinary symptoms associated with BPH.

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Description

Composition:

  • Alfuzosin (10 mg): An alpha-1 adrenergic antagonist that relaxes the smooth muscles in the prostate and bladder neck, facilitating easier urine passage.

  • Dutasteride (0.5 mg): A 5-alpha reductase inhibitor that decreases the production of dihydrotestosterone (DHT), a hormone responsible for prostate growth, thereby reducing the size of the prostate.

Indications:

Alfusin D Tablet is prescribed for the treatment of Benign Prostatic Hyperplasia (BPH), a condition characterized by an enlarged prostate gland that leads to urinary difficulties such as increased frequency, urgency, and weak urine stream.

Mechanism of Action:

The combination of Alfuzosin and Dutasteride works synergistically to:

  • Relax the muscles in the prostate and bladder neck (via Alfuzosin), improving urine flow.

  • Reduce the size of the prostate (via Dutasteride), alleviating pressure on the urethra and enhancing urinary function.

Dosage and Administration:

  • Dosage: Typically, one tablet daily, preferably after the same meal each day.

  • Administration: Swallow the tablet whole with a glass of water; do not crush or chew.

Side Effects:

Common side effects include dizziness, headache, fatigue, decreased libido, erectile dysfunction, breast tenderness, and reduced semen volume. These effects are generally mild and may subside with continued use. Consult a healthcare provider if side effects persist or worsen.

Precautions:

  • Not recommended for use in women or children.

  • Use with caution in patients with liver or kidney disorders; dose adjustments may be necessary.

  • Avoid alcohol consumption, as it may exacerbate side effects such as dizziness.

  • Inform the doctor of any history of heart disease, low blood pressure, or eye conditions.

  • Use barrier contraception during sexual activity, as Dutasteride can be present in semen and may affect a developing fetus.

SKU: CPLA23006 Category: