BEMPESTA EZ TAB

Description

Bempesta EZ 180mg/10mg Tablet combines two cholesterol-lowering agents:

• Bempedoic Acid (180 mg): An ATP citrate lyase (ACL) inhibitor that reduces cholesterol production in the liver, leading to increased LDL receptor expression and enhanced clearance of LDL-C from the bloodstream.

• Ezetimibe (10 mg): Works by inhibiting the absorption of cholesterol from the small intestine, further lowering LDL-C levels.

Indications:

Bempesta EZ is indicated for:

• Adults with primary hypercholesterolemia or mixed dyslipidemia who require additional LDL-C reduction.

• Patients who are statin-intolerant or for whom statins are contraindicated.

• Individuals already receiving separate bempedoic acid and ezetimibe tablets.

Dosage and Administration:

• The recommended dosage is one tablet (180 mg bempedoic acid + 10 mg ezetimibe) taken orally once daily.

• The tablet can be taken with or without food.

• Swallow the tablet whole; do not crush or chew.

• If a dose is missed, take it as soon as possible unless it’s almost time for the next dose. Do not double the dose.

Common Side Effects:

• Upper respiratory tract infections

• Back pain

• Abdominal discomfort

• Muscle spasms

• Fatigue

• Anemia

• Elevated liver enzymes

• Gout (due to increased uric acid levels)

Serious Side Effects:

• Tendon rupture or injury, particularly in the biceps tendon, rotator cuff, or Achilles tendon.

• Elevated uric acid levels (hyperuricemia), which may lead to gout.

Precautions:

• Contraindicated in patients with known hypersensitivity to bempedoic acid, ezetimibe, or any component of the tablet.

• Not recommended for use during pregnancy or breastfeeding.

• Use with caution in patients with severe liver or kidney problems.

• Monitor uric acid levels in patients with a history of gout.

• Avoid concomitant use with simvastatin doses greater than 40 mg daily.