AZMARDA 50MG TAB`S

Description

Azmarda 50mg Tablet is a prescription medicine used to treat patients with chronic heart failure (specifically heart failure with reduced ejection fraction – HFrEF). It contains a fixed-dose combination of:

• Sacubitril (24 mg) – a neprilysin inhibitor

• Valsartan (26 mg) – an angiotensin receptor blocker (ARB)

This dual-action combination works by relaxing blood vessels, reducing sodium levels, and decreasing the strain on the heart, leading to improved cardiac output and reduced risk of hospitalization and cardiovascular death.

Azmarda is typically used as a replacement for ACE inhibitors or ARBs in heart failure management as per ESC and AHA guidelines.

Key Features:

• Composition: Sacubitril 24 mg + Valsartan 26 mg

• Form: Oral Tablet

• Therapeutic Class: ARNI (Angiotensin Receptor-Neprilysin Inhibitor)

• Uses:

  • Chronic heart failure with reduced ejection fraction (HFrEF)

  • Improves survival and reduces hospitalizations

• Dosage: As prescribed by a cardiologist; typically twice daily

• Brand: Azmarda (Manufactured by Cipla Ltd.)

Important Information:

• Not to be used with ACE inhibitors or in patients with a history of angioedema

• Regular monitoring of blood pressure, kidney function, and potassium levels is advised

Common Side Effects:

• Dizziness or hypotension (low blood pressure)

• Increased potassium levels

• Renal impairment

• Fatigue

• Cough (less common than with ACE inhibitors)

Warnings & Precautions:

• Avoid during pregnancy and breastfeeding

• Use with caution in renal or hepatic impairment

• Not suitable for patients with hereditary angioedema