BRINZOTIM EYE DROPS

Description

Brinzotim Eye Drops are manufactured by Sun Pharmaceutical Industries Ltd and are indicated for the treatment of elevated intraocular pressure in conditions such as ocular hypertension and open-angle glaucoma.

Mechanism of Action:

• Brinzolamide (1%): A selective carbonic anhydrase inhibitor that reduces aqueous humor production by inhibiting the enzyme carbonic anhydrase II.

• Timolol (0.5%): A non-selective β-adrenergic antagonist (beta-blocker) that decreases aqueous humor production, further contributing to reduced intraocular pressure.

Together, these agents provide a complementary effect in managing elevated intraocular pressure.

Indications:

• Ocular Hypertension: Condition characterized by increased intraocular pressure without any detectable damage to the optic nerve.

• Open-Angle Glaucoma: A chronic condition where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased eye pressure.

Dosage and Administration:

• Recommended Dose: Instill 1 drop into the affected eye(s) twice daily, typically in the morning and evening.

• Administration:

  1. Wash your hands thoroughly.

  2. Tilt your head back slightly and pull down the lower eyelid to create a small pocket.

  3. Hold the dropper above the eye and squeeze out one drop.

  4. Close your eye and gently press the inner corner of the eye (near the nose) for about 2 minutes to prevent the liquid from draining away.

  5. If using other eye medications, wait at least 5 minutes before applying the next medication.

Precautions:

• Pregnancy: Consult your doctor before use; the safety during pregnancy has not been established.

• Breastfeeding: Not recommended; Brinzolamide may pass into breast milk.

• Children: Not recommended for use in children below 18 years.

• Contact Lenses: Remove soft contact lenses before use and wait at least 15 minutes before reinserting them.

• Kidney or Liver Impairment: Use with caution; consult your doctor if you have kidney or liver problems.