CENTRIVIVE 200 TAB

Description

Centrivive 200 Tablets are a proprietary blend developed by Celagenex Research (India) Pvt Ltd, combining two potent compounds:

• 3-N-Butylphthalide (NBP): Derived from celery seed extract, NBP has demonstrated neuroprotective properties, including anti-inflammatory and anti-oxidative effects, and the ability to enhance microcirculation in the brain.

• Nicotinamide Riboside Chloride: A precursor to NAD⁺, it plays a crucial role in cellular energy metabolism and has been associated with improved mitochondrial function and neuroprotection.

Mechanism of Action

Centrivive operates through multiple pathways to support neurological health:

1. Enhancement of Cerebral Blood Flow: NBP promotes neovascularization, increasing capillary density in ischemic brain regions, thereby improving oxygen and nutrient delivery .

2. Mitochondrial Protection: The formulation supports mitochondrial integrity, reducing oxidative stress and preventing neuronal apoptosis.

3. Anti-inflammatory Effects: By modulating inflammatory pathways, Centrivive helps in reducing cerebral edema and maintaining blood-brain barrier integrity.

4. Cognitive Support: The combined action of its ingredients aids in improving cognitive functions, beneficial in conditions like vascular dementia and Parkinson’s disease.

Indications

• Acute Ischemic Stroke (AIS): As an adjunct to standard therapy, Centrivive has been shown to reduce mortality and dependency rates within the first 90 days post-stroke .

• Vascular Dementia: Improves cognitive scores and daily living activities by enhancing cerebral perfusion.

• Parkinson’s Disease: Alleviates motor and non-motor symptoms by protecting dopaminergic neurons and improving mitochondrial function.

Dosage & Administration

• Recommended Dose: 200 mg capsule taken three times daily, preferably 15 minutes before meals.

• Duration: Treatment duration may vary based on the condition; for AIS, a 90-day course is commonly recommended .

Note: Always follow the prescribing physician’s guidance regarding dosage and duration.

Precautions & Side Effects

• General Tolerance: Centrivive is generally well-tolerated. Mild gastrointestinal discomfort may occur in some individuals .

• Contraindications: Not recommended for use in hemorrhagic stroke due to insufficient evidence.

• Pregnancy & Lactation: Consult a healthcare provider before use.

• Drug Interactions: Inform your doctor about all medications you are taking to avoid potential interactions.